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RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth
Adult skeletal muscle is a plastic tissue that can adapt its size to workload. Here, we show that RhoA within myofibers is needed for overload-induced hypertrophy by controlling satellite cell (SC) fusion to the growing myofibers without affecting protein synthesis. At the molecular level, we demons...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786647/ https://www.ncbi.nlm.nih.gov/pubmed/35106464 http://dx.doi.org/10.1016/j.isci.2021.103616 |