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RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth

Adult skeletal muscle is a plastic tissue that can adapt its size to workload. Here, we show that RhoA within myofibers is needed for overload-induced hypertrophy by controlling satellite cell (SC) fusion to the growing myofibers without affecting protein synthesis. At the molecular level, we demons...

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Detalles Bibliográficos
Autores principales: Noviello, Chiara, Kobon, Kassandra, Delivry, Léa, Guilbert, Thomas, Britto, Florian, Julienne, Francis, Maire, Pascal, Randrianarison-Huetz, Voahangy, Sotiropoulos, Athanassia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786647/
https://www.ncbi.nlm.nih.gov/pubmed/35106464
http://dx.doi.org/10.1016/j.isci.2021.103616