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Osteopontin accumulates in basal deposits of human eyes with age-related macular degeneration and may serve as a biomarker of aging

A common clinical phenotype of several neurodegenerative and systemic disorders including Alzheimer’s disease and atherosclerosis is the abnormal accumulation of extracellular material, which interferes with routine cellular functions. Similarly, patients with age-related macular degeneration (AMD),...

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Detalles Bibliográficos
Autores principales: Lekwuwa, Michael, Choudhary, Mayur, Lad, Eleonora M., Malek, Goldis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786662/
https://www.ncbi.nlm.nih.gov/pubmed/34389792
http://dx.doi.org/10.1038/s41379-021-00887-7