Cargando…

Osteopontin accumulates in basal deposits of human eyes with age-related macular degeneration and may serve as a biomarker of aging

A common clinical phenotype of several neurodegenerative and systemic disorders including Alzheimer’s disease and atherosclerosis is the abnormal accumulation of extracellular material, which interferes with routine cellular functions. Similarly, patients with age-related macular degeneration (AMD),...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lekwuwa, Michael, Choudhary, Mayur, Lad, Eleonora M., Malek, Goldis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786662/ https://www.ncbi.nlm.nih.gov/pubmed/34389792 http://dx.doi.org/10.1038/s41379-021-00887-7

Ejemplares similares

NURR1 expression regulates retinal pigment epithelial–mesenchymal transition and age-related macular degeneration phenotypes
por: Yao, Pei-Li, et al.
Publicado: (2022)

PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration
por: Choudhary, Mayur, et al.
Publicado: (2016)

Age-Related Macular Degeneration Revisited: From Pathology and Cellular Stress to Potential Therapies
por: Hadziahmetovic, Majda, et al.
Publicado: (2021)

Nuclear Receptor Atlases of Choroidal Tissues Reveal Candidate Receptors Associated with Age-Related Macular Degeneration
por: Peavey, Jeremy, et al.
Publicado: (2022)

Biometrics, Impact, and Significance of Basal Linear Deposit and Subretinal Drusenoid Deposit in Age-Related Macular Degeneration
por: Chen, Ling, et al.
Publicado: (2021)

Biomarkers for the Progression of Intermediate Age-Related Macular Degeneration
por: Lad, Eleonora M., et al.
Publicado: (2023)

Measuring the Contributions of Basal Laminar Deposit and Bruch's Membrane in Age-Related Macular Degeneration
por: Sura, Amol A., et al.
Publicado: (2020)

Correction: Peavey et al. Nuclear Receptor Atlases of Choroidal Tissues Reveal Candidate Receptors Associated with Age-Related Macular Degeneration. Cells 2022, 11, 2386
por: Peavey, Jeremy, et al.
Publicado: (2022)

The Aryl Hydrocarbon Receptor: A Mediator and Potential Therapeutic Target for Ocular and Non-Ocular Neurodegenerative Diseases
por: Choudhary, Mayur, et al.
Publicado: (2020)

C1q and the classical complement cascade in geographic atrophy secondary to age-related macular degeneration
por: Yednock, Ted, et al.
Publicado: (2022)

Comorbidity of age-related macular degeneration with Alzheimer’s disease: A histopathologic case-control study
por: Smilnak, Gordon J., et al.
Publicado: (2019)

Longitudinal Evaluation of Visual Function Impairments in Early and Intermediate Age-Related Macular Degeneration Patients
por: Lad, Eleonora M., et al.
Publicado: (2022)

Iron Accumulation and Lipid Peroxidation in the Aging Retina: Implication of Ferroptosis in Age-Related Macular Degeneration
por: Zhao, Tantai, et al.
Publicado: (2021)

Cerebral white matter connectivity, cognition, and age-related macular degeneration
por: Zhuang, Jie, et al.
Publicado: (2021)

Age-related macular degeneration.
por: McConnell, V., et al.
Publicado: (2005)

Age-related macular degeneration
por: Querques, Giuseppe, et al.
Publicado: (2011)

Age-related macular degeneration
por: Mathenge, Wanjiku
Publicado: (2014)

Hyperspectral autofluorescence characterization of drusen and sub-RPE deposits in age-related macular degeneration
por: Tong, Yuehong, et al.
Publicado: (2021)

Macular Thickness in Intermediate Age-Related Macular Degeneration Is Influenced by Disease Severity and Subretinal Drusenoid Deposit Presence
por: Chiang, Trent Tsun-Kang, et al.
Publicado: (2020)

Age-related macular degeneration and the aging eye
por: Ehrlich, Rita, et al.
Publicado: (2008)

Age-Related Macular Degeneration and the Aging Brain
por: Whitson, Heather, et al.
Publicado: (2021)

Association of Low Luminance Questionnaire With Objective Functional Measures in Early and Intermediate Age-Related Macular Degeneration
por: Thompson, Atalie C., et al.
Publicado: (2018)

The Association Between Subretinal Drusenoid Deposits in Older Adults in Normal Macular Health and Incident Age-Related Macular Degeneration
por: Huisingh, Carrie, et al.
Publicado: (2016)

Antecedents of Soft Drusen, the Specific Deposits of Age-Related Macular Degeneration, in the Biology of Human Macula
por: Curcio, Christine A.
Publicado: (2018)

Pharmacogenetics and Age-Related Macular Degeneration
por: Schwartz, Stephen G., et al.
Publicado: (2011)

Prevention of age-related macular degeneration
por: Wong, Ian Yat Hin, et al.
Publicado: (2010)

Angiogenin in age-related macular degeneration
por: Skeie, Jessica M., et al.
Publicado: (2011)

Pharmacotherapy for Age-Related Macular Degeneration
por: Ahmadieh, Hamid
Publicado: (2008)

Metabolomics and Age-Related Macular Degeneration
por: Brown, Connor N., et al.
Publicado: (2018)

Nanotechnology for Age-Related Macular Degeneration
por: Yang, Bo, et al.
Publicado: (2021)

Neuroprotection for Age-Related Macular Degeneration
por: Lin, Jonathan B., et al.
Publicado: (2022)

Age-Related Macular or Retinal Degeneration?
por: Gałuszka, Michalina, et al.
Publicado: (2023)

Complement factor B is critical for sub-RPE deposit accumulation in a model of Doyne honeycomb retinal dystrophy with features of age-related macular degeneration
por: Crowley, Maura A, et al.
Publicado: (2022)

Semiautomatic Segmentation of Rim Area Focal Hyperautofluorescence Predicts Progression of Geographic Atrophy Due to Dry Age-Related Macular Degeneration
por: Allingham, Michael J., et al.
Publicado: (2016)

Macular and Plasma Xanthophylls Are Higher in Age-related Macular Degeneration than in Normal Aging: Alabama Study on Early Age-related Macular Degeneration 2 Baseline
por: McGwin, Gerald, et al.
Publicado: (2022)

Macular Atrophy Development and Subretinal Drusenoid Deposits in Anti-Vascular Endothelial Growth Factor Treated Age-Related Macular Degeneration
por: Zarubina, Anna V., et al.
Publicado: (2017)

LAMELLAR MACULAR HOLES IN THE PRESENCE OF AGE-RELATED MACULAR DEGENERATION
por: Francone, Anibal, et al.
Publicado: (2020)

Impact of Prophylactic Ranibizumab to Prevent Neovascular Age-Related Macular Degeneration on Eyes With Intermediate Age-Related Macular Degeneration
por: Chan, Clement K., et al.
Publicado: (2023)

Epigenetic Age Acceleration Is Not Associated with Age-Related Macular Degeneration
por: Saptarshi, Neil, et al.
Publicado: (2021)

Machine Learning OCT Predictors of Progression from Intermediate Age-Related Macular Degeneration to Geographic Atrophy and Vision Loss
por: Lad, Eleonora M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bi8sp6iemmb5bvt056a3d2f0m7