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Patient‐derived organoids for personalized gallbladder cancer modelling and drug screening

BACKGROUND: Gallbladder carcinoma (GBC) is a relatively rare but highly aggressive cancer with late clinical detection and a poor prognosis. However, the lack of models with features consistent with human gallbladder tumours has hindered progress in pathogenic mechanisms and therapies. METHODS: We e...

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Detalles Bibliográficos
Autores principales: Yuan, Bo, Zhao, Xiaofang, Wang, Xiang, Liu, Erdong, Liu, Chunliang, Zong, Yali, Jiang, Youhai, Hou, Minghui, Chen, Yao, Chen, Lei, Zhang, Yongjie, Wang, Hongyang, Fu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786696/
https://www.ncbi.nlm.nih.gov/pubmed/35075805
http://dx.doi.org/10.1002/ctm2.678