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Zyxin protects from hypertension-induced cardiac dysfunction

Arterial hypertension causes left ventricular hypertrophy leading to dilated cardiomyopathy. Following compensatory cardiomyocyte hypertrophy, cardiac dysfunction develops due to loss of cardiomyocytes preceded or paralleled by cardiac fibrosis. Zyxin acts as a mechanotransducer in vascular cells th...

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Detalles Bibliográficos
Autores principales: Al-Hasani, Jaafar, Sens-Albert, Carla, Ghosh, Subhajit, Trogisch, Felix A., Nahar, Taslima, Friede, Prisca A. P., Reil, Jan-Christian, Hecker, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786748/
https://www.ncbi.nlm.nih.gov/pubmed/35075545
http://dx.doi.org/10.1007/s00018-022-04133-4