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Impact of hemolysis on multi-OMIC pancreatic biomarker discovery to derisk biomarker development in precision medicine studies

Cancer biomarker discovery is critically dependent on the integrity of biofluid and tissue samples acquired from study participants. Multi-omic profiling of candidate protein, lipid, and metabolite biomarkers is confounded by timing and fasting status of sample collection, participant demographics a...

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Detalles Bibliográficos
Autores principales: Searfoss, Richard, Shah, Punit, Ofori-Mensa, Kennedy, Bussberg, Valerie, Tolstikov, Vladimir, Greenwood, Bennett, Li, Hongyan, Richardson, Kris, Miller, Gregory M., DeCicco, Corinne, Granger, Elder, Rodrigues, Leonardo O., Grund, Eric M., Moser, A. James, Sarangarajan, Rangaprasad, Narain, Niven R., Kiebish, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786830/
https://www.ncbi.nlm.nih.gov/pubmed/35075163
http://dx.doi.org/10.1038/s41598-022-05152-8