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Integration of single-cell transcriptomes and chromatin landscapes reveals regulatory programs driving pharyngeal organ development

Maldevelopment of the pharyngeal endoderm, an embryonic tissue critical for patterning of the pharyngeal region and ensuing organogenesis, ultimately contributes to several classes of human developmental syndromes and disorders. Such syndromes are characterized by a spectrum of phenotypes that curre...

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Detalles Bibliográficos
Autores principales: Magaletta, Margaret E., Lobo, Macrina, Kernfeld, Eric M., Aliee, Hananeh, Huey, Jack D., Parsons, Teagan J., Theis, Fabian J., Maehr, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786836/
https://www.ncbi.nlm.nih.gov/pubmed/35075189
http://dx.doi.org/10.1038/s41467-022-28067-4