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Effect of interleukin-1 blockade with anakinra on leukocyte count in patients with ST-segment elevation acute myocardial infarction

Leukocytosis is a common finding in patients with ST elevation myocardial infarction (STEMI) and portends a poor prognosis. Interleukin 1-β regulates leukopoiesis and pre-clinical studies suggest that anakinra (recombinant human interleukin-1 [IL-1] receptor antagonist) suppresses leukocytosis in my...

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Detalles Bibliográficos
Autores principales: Del Buono, Marco Giuseppe, Damonte, Juan Ignacio, Trankle, Cory R., Kadariya, Dinesh, Carbone, Salvatore, Thomas, Georgia, Turlington, Jeremy, Markley, Roshanak, Canada, Justin M., Biondi‐Zoccai, Giuseppe G., Kontos, Michael C., Van Tassell, Benjamin W., Abbate, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786840/
https://www.ncbi.nlm.nih.gov/pubmed/35075216
http://dx.doi.org/10.1038/s41598-022-05374-w