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A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies

As a result of the SARS-CoV-2 pandemic numerous scientific groups have generated antibodies against a single target: the CoV-2 spike antigen. This has provided an unprecedented opportunity to compare the efficacy of different methods and the specificities and qualities of the antibodies generated by...

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Detalles Bibliográficos
Autores principales: Ferrara, Fortunato, Erasmus, M. Frank, D’Angelo, Sara, Leal-Lopes, Camila, Teixeira, André A., Choudhary, Alok, Honnen, William, Calianese, David, Huang, Deli, Peng, Linghan, Voss, James E., Nemazee, David, Burton, Dennis R., Pinter, Abraham, Bradbury, Andrew R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786865/
https://www.ncbi.nlm.nih.gov/pubmed/35075126
http://dx.doi.org/10.1038/s41467-021-27799-z