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Impaired selective renal filtration captured by eGFR(cysC)/eGFR(crea) ratio is associated with mortality in a population based cohort of older women

Deranged renal filtration of mid-sized (5–30 kDa) compared to smaller molecules (< 0.9 kDa) results in increased plasma levels of cystatin C (cysC) compared to creatinine resulting in a low eGFR(cysC)/eGFR(crea) ratio. A ratio below 0.6 or 0.7, is termed shrunken pore syndrome (SPS), which in pat...

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Detalles Bibliográficos
Autores principales: Malmgren, Linnea, McGuigan, Fiona E., Christensson, Anders, Akesson, Kristina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786879/
https://www.ncbi.nlm.nih.gov/pubmed/35075286
http://dx.doi.org/10.1038/s41598-022-05320-w