Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase

Toxoplasma gondii commonly infects humans and while most infections are controlled by the immune response, currently approved drugs are not capable of clearing chronic infection in humans. Hence, approximately one third of the world’s human population is at risk of reactivation, potentially leading...

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Detalles Bibliográficos
Autores principales: Radke, Joshua B., Melillo, Bruno, Mittal, Payal, Sharma, Manmohan, Sharma, Amit, Fu, Yong, Uddin, Taher, Gonse, Arthur, Comer, Eamon, Schreiber, Stuart L., Gupta, Anil K., Chatterjee, Arnab K., Sibley, L. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786932/
https://www.ncbi.nlm.nih.gov/pubmed/35075105
http://dx.doi.org/10.1038/s41467-022-28108-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786932/
https://www.ncbi.nlm.nih.gov/pubmed/35075105
http://dx.doi.org/10.1038/s41467-022-28108-y

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