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Genetic Predisposition to Low-Density Lipoprotein Cholesterol May Increase Risks of Both Individual and Familial Alzheimer's Disease

Background: Previous observational studies provided conflicting results on the association between low-density lipoprotein cholesterol (LDL-C) level and the risk of Alzheimer's disease (AD). Objective: We used two-sample Mendelian randomization (MR) study to explore the causal associations betw...

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Detalles Bibliográficos
Autores principales: Tan, Jiang-Shan, Hu, Meng-Jin, Yang, Yan-Min, Yang, Yue-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787049/
https://www.ncbi.nlm.nih.gov/pubmed/35087849
http://dx.doi.org/10.3389/fmed.2021.798334