Constipation Caused by Anti-calcitonin Gene-Related Peptide Migraine Therapeutics Explained by Antagonism of Calcitonin Gene-Related Peptide’s Motor-Stimulating and Prosecretory Function in the Intestine

The development of small-molecule calcitonin gene-related peptide (CGRP) receptor antagonists (gepants) and of monoclonal antibodies targeting the CGRP system has been a major advance in the management of migraine. In the randomized controlled trials before regulatory approval, the safety of these a...

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Detalles Bibliográficos
Autores principales: Holzer, Peter, Holzer-Petsche, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787053/
https://www.ncbi.nlm.nih.gov/pubmed/35087426
http://dx.doi.org/10.3389/fphys.2021.820006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787053/
https://www.ncbi.nlm.nih.gov/pubmed/35087426
http://dx.doi.org/10.3389/fphys.2021.820006

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