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Pleckstrin Levels Are Increased in Patients with Chronic Periodontitis and Regulated via the MAP Kinase-p38α Signaling Pathway in Gingival Fibroblasts

Chronic periodontitis (CP) is a bacteria-driven inflammatory disease characterized by the breakdown of gingival tissue, the periodontal ligament, and alveolar bone, leading ultimately to tooth loss. We previously reported the pleckstrin gene (PLEK) to be highly upregulated in gingival tissue of pati...

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Detalles Bibliográficos
Autores principales: Alim, M. Abdul, Njenda, Duncan, Lundmark, Anna, Kaminska, Marta, Jansson, Leif, Eriksson, Kaja, Kats, Anna, Johannsen, Gunnar, Arvidsson, Catalin Koro, Mydel, Piotr M., Yucel-Lindberg, Tülay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787058/
https://www.ncbi.nlm.nih.gov/pubmed/35087525
http://dx.doi.org/10.3389/fimmu.2021.801096