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Promoter DNA Methylation in GWAS-Identified Genes as Potential Functional Elements for Blood Pressure: An Observational and Mendelian Randomization Study

Genome-wide association studies have identified numerous genetic loci for blood pressure (BP). However, the relationships of functional elements inside these loci with BP are not fully understood. This study represented an effort to determine if promoter DNA methylations inside BP-associated loci we...

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Detalles Bibliográficos
Autores principales: Zhang, Huan, Wang, Aili, Xu, Tan, Mo, Xingbo, Zhang, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787193/
https://www.ncbi.nlm.nih.gov/pubmed/35087571
http://dx.doi.org/10.3389/fgene.2021.791146