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Novel Molecular Determinants of Response or Resistance to Immune Checkpoint Inhibitor Therapies in Melanoma

BACKGROUND: Immune checkpoint inhibitor (ICI) therapy dramatically prolongs melanoma survival. Currently, the identified ICI markers are sometimes ineffective. The objective of this study was to identify novel determinants of ICI efficacy. METHODS: We comprehensively curated pretreatment somatic mut...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjing, Kong, Yujia, Li, Yuting, Shi, Fuyan, Lyu, Juncheng, Sheng, Chao, Wang, Suzhen, Wang, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787219/
https://www.ncbi.nlm.nih.gov/pubmed/35087523
http://dx.doi.org/10.3389/fimmu.2021.798474