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The Crosstalk Between Malignant Cells and Tumor-Promoting Immune Cells Relevant to Immunotherapy in Pancreatic Ductal Adenocarcinoma

Background: Pancreatic ductal adenocarcinoma (PDAC) is dominated by an immunosuppressive microenvironment, which makes immune checkpoint blockade (ICB) often non-responsive. Understanding the mechanisms by which PDAC forms an immunosuppressive microenvironment is important for the development of new...

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Detalles Bibliográficos
Autores principales: Liu, Xuefei, Luo, Ziwei, Ren, Xuechen, Chen, Zhihang, Bao, Xiaoqiong, Zheng, Jianghua, Zuo, Zhixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787220/
https://www.ncbi.nlm.nih.gov/pubmed/35087839
http://dx.doi.org/10.3389/fcell.2021.821232