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Aberrant GATA2 Activation in Pediatric B-Cell Acute Lymphoblastic Leukemia
GATA2 is a transcription factor that is critical for the generation and survival of hematopoietic stem cells (HSCs). It also plays an important role in the regulation of myeloid differentiation. Accordingly, GATA2 expression is restricted to HSCs and hematopoietic progenitors as well as early erythr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787225/ https://www.ncbi.nlm.nih.gov/pubmed/35087776 http://dx.doi.org/10.3389/fped.2021.795529 |