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Pharmacological Targeting of STING-Dependent IL-6 Production in Cancer Cells
Activation of the STING pathway upon genotoxic treatment of cancer cells has been shown to lead to anti-tumoral effects, mediated through the acute production of interferon (IFN)-β. Conversely, the pathway also correlates with the expression of NF-κB-driven pro-tumorigenic genes, but these associati...
Autores principales: | Al-Asmari, Sumaiah S., Rajapakse, Aleksandra, Ullah, Tomalika R., Pépin, Geneviève, Croft, Laura V., Gantier, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787270/ https://www.ncbi.nlm.nih.gov/pubmed/35087822 http://dx.doi.org/10.3389/fcell.2021.709618 |
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