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GABA(A) Receptors in Astrocytes Are Targets for Commonly Used Intravenous and Inhalational General Anesthetic Drugs

Background: Perioperative neurocognitive disorders (PNDs) occur commonly in older patients after anesthesia and surgery. Treating astrocytes with general anesthetic drugs stimulates the release of soluble factors that increase the cell-surface expression and function of GABA(A) receptors in neurons....

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Detalles Bibliográficos
Autores principales: Chung, Woosuk, Wang, Dian-Shi, Khodaei, Shahin, Pinguelo, Arsene, Orser, Beverley A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787299/
https://www.ncbi.nlm.nih.gov/pubmed/35087395
http://dx.doi.org/10.3389/fnagi.2021.802582