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GABA(A) Receptors in Astrocytes Are Targets for Commonly Used Intravenous and Inhalational General Anesthetic Drugs
Background: Perioperative neurocognitive disorders (PNDs) occur commonly in older patients after anesthesia and surgery. Treating astrocytes with general anesthetic drugs stimulates the release of soluble factors that increase the cell-surface expression and function of GABA(A) receptors in neurons....
Autores principales: | Chung, Woosuk, Wang, Dian-Shi, Khodaei, Shahin, Pinguelo, Arsene, Orser, Beverley A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787299/ https://www.ncbi.nlm.nih.gov/pubmed/35087395 http://dx.doi.org/10.3389/fnagi.2021.802582 |
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