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Nano‐Enabled Reposition of Proton Pump Inhibitors for TLR Inhibition: Toward A New Targeted Nanotherapy for Acute Lung Injury

Toll‐like receptor (TLR) activation in macrophages plays a critical role in the pathogenesis of acute lung injury (ALI). While TLR inhibition is a promising strategy to control the overwhelming inflammation in ALI, there still lacks effective TLR inhibitors for clinical uses to date. A unique class...

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Detalles Bibliográficos
Autores principales: Sun, Liya, Liu, Yuan, Liu, Xiali, Wang, Rui, Gong, Jiameng, Saferali, Aabida, Gao, Wei, Ma, Aying, Ma, Huiqiang, Turvey, Stuart E., Fung, Shan‐Yu, Yang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787384/
https://www.ncbi.nlm.nih.gov/pubmed/34816630
http://dx.doi.org/10.1002/advs.202104051