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Engineered Small Extracellular Vesicles as a FGL1/PD‐L1 Dual‐Targeting Delivery System for Alleviating Immune Rejection

There is an urgent need for developing new immunosuppressive agents due to the toxicity of long‐term use of broad immunosuppressive agents after organ transplantation. Comprehensive sample analysis revealed dysregulation of FGL1/LAG‐3 and PD‐L1/PD‐1 immune checkpoints in allogeneic heart transplanta...

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Detalles Bibliográficos
Autores principales: Tsai, Hsiang‐i, Wu, Yingyi, Liu, Xiaoyan, Xu, Zhanxue, Liu, Longshan, Wang, Changxi, Zhang, Huanxi, Huang, Yisheng, Wang, Linglu, Zhang, Weixian, Su, Dandan, Khan, Fahim Ullah, Zhu, Xiaofeng, Yang, Rongya, Pang, Yuxin, Eriksson, John E., Zhu, Haitao, Wang, Dongqing, Jia, Bo, Cheng, Fang, Chen, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787398/
https://www.ncbi.nlm.nih.gov/pubmed/34738731
http://dx.doi.org/10.1002/advs.202102634