Cargando…

Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High‐Fat Diet‐Induced Obesity Mediated by Autophagy

Neuronal primary cilia are crucial for body weight maintenance. Type III adenylyl cyclase (AC3) is abundantly enriched in neuronal cilia, and mice with global AC3 ablation are obese. However, whether AC3 regulates body weight through its ciliary expression and the mechanism underlying this potential...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Dong, Wu, Xiangbo, Wang, Weina, Zhou, Yanfen, Wang, Zhenshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787410/
https://www.ncbi.nlm.nih.gov/pubmed/34783461
http://dx.doi.org/10.1002/advs.202102568