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Directing Cholangiocyte Morphogenesis in Natural Biomaterial Scaffolds

Patients with Alagille syndrome carry monogenic mutations in the Notch signaling pathway and face complications such as jaundice and cholestasis. Given the presence of intrahepatic ductopenia in these patients, Notch2 receptor signaling is implicated in driving normal biliary development and downstr...

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Detalles Bibliográficos
Autores principales: Smith, Quinton, Bays, Jennifer, Li, Linqing, Shareef, Haniyah, Chen, Christopher S., Bhatia, Sangeeta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787431/
https://www.ncbi.nlm.nih.gov/pubmed/34786888
http://dx.doi.org/10.1002/advs.202102698