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Directing Cholangiocyte Morphogenesis in Natural Biomaterial Scaffolds
Patients with Alagille syndrome carry monogenic mutations in the Notch signaling pathway and face complications such as jaundice and cholestasis. Given the presence of intrahepatic ductopenia in these patients, Notch2 receptor signaling is implicated in driving normal biliary development and downstr...
Autores principales: | Smith, Quinton, Bays, Jennifer, Li, Linqing, Shareef, Haniyah, Chen, Christopher S., Bhatia, Sangeeta N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787431/ https://www.ncbi.nlm.nih.gov/pubmed/34786888 http://dx.doi.org/10.1002/advs.202102698 |
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