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DOCK2 regulates antifungal immunity by regulating RAC GTPase activity

Fungal infections cause ~1.5 million deaths each year worldwide, and the mortality rate of disseminated candidiasis currently exceeds that of breast cancer and malaria. The major reasons for the high mortality of candidiasis are the limited number of antifungal drugs and the emergence of drug-resist...

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Detalles Bibliográficos
Autores principales: Ma, Xiaojian, Tan, Xi, Yu, Bingbing, Sun, Wanwei, Wang, Heping, Hu, Huijun, Du, Yanyun, He, Ruirui, Gao, Ru, Peng, Qianwen, Cui, Zhihui, Pan, Ting, Feng, Xiong, Wang, Junhan, Xu, Chengqi, Zhu, Bin, Liu, Wei, Wang, Chenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787451/
https://www.ncbi.nlm.nih.gov/pubmed/35079145
http://dx.doi.org/10.1038/s41423-021-00835-0