Coxiella burnetii Sterol-Modifying Protein Stmp1 Regulates Cholesterol in the Intracellular Niche

Coxiella burnetii replicates in a phagolysosome-like vacuole called the Coxiella-containing vacuole (CCV). While host cholesterol readily traffics to the CCV, cholesterol accumulation leads to CCV acidification and bacterial death. Thus, bacterial regulation of CCV cholesterol content is essential f...

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Detalles Bibliográficos
Autores principales: Clemente, Tatiana M., Ratnayake, Rochelle, Samanta, Dhritiman, Augusto, Leonardo, Beare, Paul A., Heinzen, Robert A., Gilk, Stacey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787468/
https://www.ncbi.nlm.nih.gov/pubmed/35073737
http://dx.doi.org/10.1128/mbio.03073-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787468/
https://www.ncbi.nlm.nih.gov/pubmed/35073737
http://dx.doi.org/10.1128/mbio.03073-21

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