Cargando…

Inhibiting Mycobacterium abscessus Cell Wall Synthesis: Using a Novel Diazabicyclooctane β-Lactamase Inhibitor To Augment β-Lactam Action

Mycobacterium abscessus (Mab) infections are a growing menace to the health of many patients, especially those suffering from structural lung disease and cystic fibrosis. With multidrug resistance a common feature and a growing understanding of peptidoglycan synthesis in Mab, it is advantageous to i...

Descripción completa

Detalles Bibliográficos
Autores principales: Dousa, Khalid M., Nguyen, David C., Kurz, Sebastian G., Taracila, Magdalena A., Bethel, Christopher R., Schinabeck, William, Kreiswirth, Barry N., Brown, Sheldon T., Boom, W. Henry, Hotchkiss, Richard S., Remy, Kenneth E., Jacono, Frank J., Daley, Charles L., Holland, Steven M., Miller, Alita A., Bonomo, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787486/
https://www.ncbi.nlm.nih.gov/pubmed/35073757
http://dx.doi.org/10.1128/mbio.03529-21