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Identification of Key Determinants of Cerebral Malaria Development and Inhibition Pathways

Cerebral malaria (CM), coma caused by Plasmodium falciparum-infected red blood cells (iRBCs), is the deadliest complication of malaria. The mechanisms that lead to CM development are incompletely understood. Here we report on the identification of activation and inhibition pathways leading to mouse...

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Detalles Bibliográficos
Autores principales: Cha, Sung-Jae, Yu, Xiang, Gregory, Brian D., Lee, Yong Seok, Ishino, Tomoko, Opoka, Robert O., John, Chandy C., Jacobs-Lorena, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787489/
https://www.ncbi.nlm.nih.gov/pubmed/35073748
http://dx.doi.org/10.1128/mbio.03708-21