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Autofluorescent Organelles Within the Retinal Pigment Epithelium in Human Donor Eyes With and Without Age-Related Macular Degeneration

PURPOSE: Human retinal pigment epithelium (RPE) cells contain lipofuscin, melanolipofuscin, and melanosome organelles that impact clinical autofluorescence (AF) imaging. Here, we quantified the effect of age-related macular degeneration (AMD) on granule count and histologic AF of RPE cell bodies. ME...

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Detalles Bibliográficos
Autores principales: Bermond, Katharina, von der Emde, Leon, Tarau, Ioana-Sandra, Bourauel, Leonie, Heintzmann, Rainer, Holz, Frank G., Curcio, Christine A., Sloan, Kenneth R., Ach, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787573/
https://www.ncbi.nlm.nih.gov/pubmed/35050307
http://dx.doi.org/10.1167/iovs.63.1.23