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The Need to Unravel Arsenolipid Transformations in Humans
The main source of arsenic exposure to humans worldwide is the diet, in particular, drinking water, rice, and seafood. Although arsenic is often considered toxic, it can exist in food as more than 300 chemical species with different toxicities. This diversity makes it difficult for food safety and h...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Mary Ann Liebert, Inc., publishers
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787705/ https://www.ncbi.nlm.nih.gov/pubmed/34941367 http://dx.doi.org/10.1089/dna.2021.0476 |
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author | Chávez-Capilla, Teresa |
author_facet | Chávez-Capilla, Teresa |
author_sort | Chávez-Capilla, Teresa |
collection | PubMed |
description | The main source of arsenic exposure to humans worldwide is the diet, in particular, drinking water, rice, and seafood. Although arsenic is often considered toxic, it can exist in food as more than 300 chemical species with different toxicities. This diversity makes it difficult for food safety and health authorities to regulate arsenic levels in food, which are currently based on a few arsenic species. Of particular interest are arsenolipids, a type of arsenic species widely found in seafood. Emerging evidence indicates that there are risks associated with human exposure to arsenolipids (e.g., accumulation in breast milk, ability to cross the blood–brain barrier and accumulate in the brain, and potential development of neurodegenerative disorders). Still, more research is needed to fully understand the impact of arsenolipid exposure, which requires establishing interdisciplinary collaborations. |
format | Online Article Text |
id | pubmed-8787705 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Mary Ann Liebert, Inc., publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-87877052022-01-25 The Need to Unravel Arsenolipid Transformations in Humans Chávez-Capilla, Teresa DNA Cell Biol Section D: The interplay Between Health and the Environment The main source of arsenic exposure to humans worldwide is the diet, in particular, drinking water, rice, and seafood. Although arsenic is often considered toxic, it can exist in food as more than 300 chemical species with different toxicities. This diversity makes it difficult for food safety and health authorities to regulate arsenic levels in food, which are currently based on a few arsenic species. Of particular interest are arsenolipids, a type of arsenic species widely found in seafood. Emerging evidence indicates that there are risks associated with human exposure to arsenolipids (e.g., accumulation in breast milk, ability to cross the blood–brain barrier and accumulate in the brain, and potential development of neurodegenerative disorders). Still, more research is needed to fully understand the impact of arsenolipid exposure, which requires establishing interdisciplinary collaborations. Mary Ann Liebert, Inc., publishers 2022-01-01 2022-01-12 /pmc/articles/PMC8787705/ /pubmed/34941367 http://dx.doi.org/10.1089/dna.2021.0476 Text en © Teresa Chávez-Capilla 2022; Published by Mary Ann Liebert, Inc. https://creativecommons.org/licenses/by/4.0/This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Section D: The interplay Between Health and the Environment Chávez-Capilla, Teresa The Need to Unravel Arsenolipid Transformations in Humans |
title | The Need to Unravel Arsenolipid Transformations in Humans |
title_full | The Need to Unravel Arsenolipid Transformations in Humans |
title_fullStr | The Need to Unravel Arsenolipid Transformations in Humans |
title_full_unstemmed | The Need to Unravel Arsenolipid Transformations in Humans |
title_short | The Need to Unravel Arsenolipid Transformations in Humans |
title_sort | need to unravel arsenolipid transformations in humans |
topic | Section D: The interplay Between Health and the Environment |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787705/ https://www.ncbi.nlm.nih.gov/pubmed/34941367 http://dx.doi.org/10.1089/dna.2021.0476 |
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