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Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems

[Image: see text] Regional brain distribution and metabolism of neurotransmitters and their response to drug treatment are fundamentally important for understanding the central effects of neuroactive substances. We used matrix-assisted laser desorption/ionization mass spectrometry imaging in combina...

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Detalles Bibliográficos
Autores principales: Fridjonsdottir, Elva, Vallianatou, Theodosia, Mantas, Ioannis, Shariatgorji, Reza, Nilsson, Anna, Schembri, Luke S., Odell, Luke R., Svenningsson, Per, Andrén, Per E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787750/
https://www.ncbi.nlm.nih.gov/pubmed/34932310
http://dx.doi.org/10.1021/acschembio.1c00803