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Impact of Cystic Fibrosis Transmembrane Conductance Regulator Therapy on Chronic Rhinosinusitis and Health Status: Deep Learning CT Analysis and Patient-reported Outcomes

RATIONALE: Elexacaftor, tezacaftor, and ivacaftor (ETI) in triple combination improves pulmonary health for people with cystic fibrosis (PwCF). However, its impact on objective measures of sinus disease and health utility is unestablished. OBJECTIVES: To evaluate the impact of ETI on chronic rhinosi...

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Detalles Bibliográficos
Autores principales: Beswick, Daniel M., Humphries, Stephen M., Balkissoon, Connor D., Strand, Matthew, Vladar, Eszter K., Lynch, David A., Taylor-Cousar, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787790/
https://www.ncbi.nlm.nih.gov/pubmed/34436985
http://dx.doi.org/10.1513/AnnalsATS.202101-057OC