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Facile and Scalable Methodology for the Pyrrolo[2,1-f][1,2,4]triazine of Remdesivir

[Image: see text] Pyrrolo[2,1-f][1,2,4]triazine (1) is an important regulatory starting material in the production of the antiviral drug remdesivir. Compound 1 was produced through a newly developed synthetic methodology utilizing simple building blocks such as pyrrole, chloramine, and formamidine a...

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Detalles Bibliográficos
Autores principales: Roy, Sarabindu, Yadaw, Ajay, Roy, Subho, Sirasani, Gopal, Gangu, Aravind, Brown, Jack D., Armstrong, Joseph D., Stringham, Rodger W., Gupton, B. Frank, Senanayake, Chris H., Snead, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787819/
https://www.ncbi.nlm.nih.gov/pubmed/35095258
http://dx.doi.org/10.1021/acs.oprd.1c00071