Neuropilin-1 is over-expressed in claudin-low breast cancer and promotes tumor progression through acquisition of stem cell characteristics and RAS/MAPK pathway activation

BACKGROUND: Triple-negative breast cancers (TNBC) have a relatively poor prognosis and responses to targeted therapies. Between 25 and 39% of TNBCs are claudin-low, a poorly differentiated subtype enriched for mesenchymal, stem cell and mitogen-activated signaling pathways. We investigated the role...

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Detalles Bibliográficos
Autores principales: Tang, Yu Hin, Rockstroh, Anja, Sokolowski, Kamil A., Lynam, Layla-Rose, Lehman, Melanie, Thompson, Erik W., Gregory, Philip A., Nelson, Colleen C., Volpert, Marianna, Hollier, Brett G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787892/
https://www.ncbi.nlm.nih.gov/pubmed/35078508
http://dx.doi.org/10.1186/s13058-022-01501-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787892/
https://www.ncbi.nlm.nih.gov/pubmed/35078508
http://dx.doi.org/10.1186/s13058-022-01501-7

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