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Model-based stratification of progression along the Alzheimer disease continuum highlights the centrality of biomarker synergies

BACKGROUND: The progression rates of Alzheimer’s disease (AD) are variable and dynamic, yet the mechanisms that contribute to heterogeneity in progression rates remain ill-understood. Particularly, the role of synergies in pathological processes reflected by biomarkers for amyloid-beta (‘A’), tau (‘...

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Detalles Bibliográficos
Autores principales: Sadiq, Muhammad Usman, Kwak, Kichang, Dayan, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787915/
https://www.ncbi.nlm.nih.gov/pubmed/35073974
http://dx.doi.org/10.1186/s13195-021-00941-1