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Exosome-liposome hybrid nanoparticle codelivery of TP and miR497 conspicuously overcomes chemoresistant ovarian cancer

BACKGROUND: Although cisplatin-based chemotherapy has been used as the first-line treatment for ovarian cancer (OC), tumor cells develop resistance to cisplatin during treatment, causing poor prognosis in OC patients. Studies have demonstrated that overactivation of the phosphatidylinositol 3-kinase...

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Detalles Bibliográficos
Autores principales: Li, Longxia, He, Di, Guo, Qianqian, Zhang, Zhiyoung, Ru, Dan, Wang, Liting, Gong, Ke, Liu, Fangfang, Duan, Yourong, Li, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787930/
https://www.ncbi.nlm.nih.gov/pubmed/35078498
http://dx.doi.org/10.1186/s12951-022-01264-5