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Integrated 5-hydroxymethylcytosine and fragmentation signatures as enhanced biomarkers in lung cancer
BACKGROUND: Lung cancer is one of most common cancers worldwide, with a 5-year survival rate of less than 20%, which is mainly due to late-stage diagnosis. Noninvasive methods using 5-hydroxymethylation of cytosine (5hmC) modifications and fragmentation profiles from 5hmC cell-free DNA (cfDNA) seque...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787948/ https://www.ncbi.nlm.nih.gov/pubmed/35073982 http://dx.doi.org/10.1186/s13148-022-01233-7 |