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Exacerbated post‐infarct pathological myocardial remodelling in diabetes is associated with impaired autophagy and aggravated NLRP3 inflammasome activation

BACKGROUND: Diabetes mellitus (DM) patients surviving myocardial infarction (MI) have substantially higher mortality due to the more frequent development of subsequent pathological myocardial remodelling and concomitant functional deterioration. This study investigates the molecular pathways underly...

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Detalles Bibliográficos
Autores principales: Mao, Shuai, Chen, Peipei, Pan, Wenjun, Gao, Lei, Zhang, Minzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787965/
https://www.ncbi.nlm.nih.gov/pubmed/34964299
http://dx.doi.org/10.1002/ehf2.13754