Green tea-derived theabrownin induces cellular senescence and apoptosis of hepatocellular carcinoma through p53 signaling activation and bypassed JNK signaling suppression

BACKGROUND: Theabrownin (TB) is a bioactive component of tea and has been reported to exert effects against many human cancers, but its efficacy and mechanism on hepatocellular carcinoma (HCC) with different p53 genotypes remains unclarified. METHODS: MTT assay, DAPI staining, flow cytometry and SA-...

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Detalles Bibliográficos
Autores principales: Xu, Jiaan, Xiao, Xiujuan, Yan, Bo, Yuan, Qiang, Dong, Xiaoqiao, Du, Quan, Zhang, Jin, Shan, Letian, Ding, Zhishan, Zhou, Li, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788116/
https://www.ncbi.nlm.nih.gov/pubmed/35078476
http://dx.doi.org/10.1186/s12935-022-02468-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788116/
https://www.ncbi.nlm.nih.gov/pubmed/35078476
http://dx.doi.org/10.1186/s12935-022-02468-3

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