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Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration
Glutamate is the most commonly engaged neurotransmitter in the mammalian central nervous system, acting to mediate excitatory neurotransmission. However, high levels of glutamatergic input elicit excitotoxicity, contributing to neuronal cell death following acute brain injuries such as stroke and tr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788129/ https://www.ncbi.nlm.nih.gov/pubmed/35078537 http://dx.doi.org/10.1186/s40035-021-00278-7 |