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Evolution under Spatially Heterogeneous Selection in Solid Tumors

Spatial genetic and phenotypic diversity within solid tumors has been well documented. Nevertheless, how this heterogeneity affects temporal dynamics of tumorigenesis has not been rigorously examined because solid tumors do not evolve as the standard population genetic model due to the spatial const...

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Detalles Bibliográficos
Autores principales: Li, Guanghao, Yang, Zuyu, Wu, Dafei, Liu, Sixue, Li, Xuening, Li, Tao, Li, Yawei, Liang, Liji, Zou, Weilong, Wu, Chung-I, Wang, Hurng-Yi, Lu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788224/
https://www.ncbi.nlm.nih.gov/pubmed/34850073
http://dx.doi.org/10.1093/molbev/msab335