H7N9 virus infection triggers lethal cytokine storm by activating gasdermin E-mediated pyroptosis of lung alveolar epithelial cells

The H7N9 influenza virus emerged in China in 2013, causing more than 1560 human infections, 39% of which were fatal. A ‘cytokine storm’ in the lungs of H7N9 patients has been linked to a poor prognosis and death; however, the underlying mechanism that triggers the cytokine storm is unknown. Here, we...

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Detalles Bibliográficos
Autores principales: Wan, Xiaopeng, Li, Jiqing, Wang, Yupeng, Yu, Xiaofei, He, Xijun, Shi, Jianzhong, Deng, Guohua, Zeng, Xianying, Tian, Guobin, Li, Yanbing, Jiang, Yongping, Guan, Yuntao, Li, Chengjun, Shao, Feng, Chen, Hualan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788236/
https://www.ncbi.nlm.nih.gov/pubmed/35087672
http://dx.doi.org/10.1093/nsr/nwab137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788236/
https://www.ncbi.nlm.nih.gov/pubmed/35087672
http://dx.doi.org/10.1093/nsr/nwab137

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