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Toxic clozapine level as first indication of severe, acute infection

BACKGROUND: Clozapine levels can be influenced by many factors, including pharmacogenomic variability, pharmacokinetic drug interactions, and infection/inflammation. The concentration-to-dose ratio (C/D), a measure of a medication's rate of metabolism and clearance, may increase during an acute...

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Detalles Bibliográficos
Autores principales: Davis, Erica A. K., Hightower, Tyler, Cinnamon, Katherine Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: College of Psychiatric & Neurologic Pharmacists 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788300/
https://www.ncbi.nlm.nih.gov/pubmed/35116212
http://dx.doi.org/10.9740/mhc.2022.01.045