Clinical and molecular characteristics associated with response to therapeutic PD-1/PD-L1 inhibition in advanced Merkel cell carcinoma

BACKGROUND: Based on its viral-associated or UV-associated carcinogenesis, Merkel cell carcinoma (MCC) is a highly immunogenic skin cancer. Thus, clinically evident MCC occurs either in immuno-compromised patients or based on tumor-intrinsic immune escape mechanisms. This notion may explain that alt...

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Detalles Bibliográficos
Autores principales: Spassova, Ivelina, Ugurel, Selma, Kubat, Linda, Zimmer, Lisa, Terheyden, Patrick, Mohr, Annalena, Björn Andtback, Hannah, Villabona, Lisa, Leiter, Ulrike, Eigentler, Thomas, Loquai, Carmen, Hassel, Jessica C, Gambichler, Thilo, Haferkamp, Sebastian, Mohr, Peter, Pfoehler, Claudia, Heinzerling, Lucie, Gutzmer, Ralf, Utikal, Jochen S, Horny, Kai, Schildhaus, Hans-Ulrich, Habermann, Daniel, Hoffmann, Daniel, Schadendorf, Dirk, Becker, Jürgen Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788332/
https://www.ncbi.nlm.nih.gov/pubmed/35074902
http://dx.doi.org/10.1136/jitc-2021-003198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788332/
https://www.ncbi.nlm.nih.gov/pubmed/35074902
http://dx.doi.org/10.1136/jitc-2021-003198

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