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Synthesized nano particles of glimepiride via spray freezing into cryogenic liquid: characterization, antidiabetic activity, and bioavailability

The aim of this work was to formulate glimepiride (class II drug) which is characterized by low solubility and high permeability as nanostructured particles using a cryogenic technique with an aid of water-soluble polymer to improve its aqueous solubility and hence its bioavailability. 27 formula of...

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Detalles Bibliográficos
Autores principales: Gaber, Dalia A., Alhuwaymili, Abdulrahman S., Alhawas, Hessah S., Almutiri, Alhnouf A., Alsubaiyel, Amal M., Abdoun, Siham A., Almutairi, Reem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788345/
https://www.ncbi.nlm.nih.gov/pubmed/35068278
http://dx.doi.org/10.1080/10717544.2021.2018524