Loss of Planar Cell Polarity Effector Fuzzy Causes Renal Hypoplasia by Disrupting Several Signaling Pathways

In vertebrates, the planar cell polarity (PCP) pathway regulates tissue morphogenesis during organogenesis, including the kidney. Mutations in human PCP effector proteins have been associated with severe syndromic ciliopathies. Importantly, renal hypoplasia has been reported in some patients. Howeve...

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Detalles Bibliográficos
Autores principales: Wang, Irene-Yanran, Chung, Chen-Fang, Babayeva, Sima, Sogomonian, Tamara, Torban, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788523/
https://www.ncbi.nlm.nih.gov/pubmed/35076510
http://dx.doi.org/10.3390/jdb10010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788523/
https://www.ncbi.nlm.nih.gov/pubmed/35076510
http://dx.doi.org/10.3390/jdb10010001

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