Engineering an Enhanced EGFR Engager: Humanization of Cetuximab for Improved Developability

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase whose proliferative effects can contribute to the development of many types of solid tumors when overexpressed. For this reason, EGFR inhibitors such as cetuximab can play an important role in treating cancers such as colorect...

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Detalles Bibliográficos
Autores principales: Goulet, Dennis R., Chatterjee, Soumili, Lee, Wai-Ping, Waight, Andrew B., Zhu, Yi, Mak, Amanda Nga-Sze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788544/
https://www.ncbi.nlm.nih.gov/pubmed/35076451
http://dx.doi.org/10.3390/antib11010006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788544/
https://www.ncbi.nlm.nih.gov/pubmed/35076451
http://dx.doi.org/10.3390/antib11010006

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